Greg Selkoe was born in Boston, Massachusetts and raised in the Jamaica Plain neighborhood.
Selkoe began Karmaloop from his parents' basement in 2000.
He went to the The Winchendon School, a boarding school in Winchendon, Massachusetts. Selkoe received his undergraduate degree from Rollins College in Winter Park, Florida. After graduation from Rollins and before starting Karmaloop, Selkoe worked for the City of Boston for three years at the Boston Redevelopment Authority. After starting Karmaloop, Selkoe continued his education at The Kennedy School of Government at Harvard University and completed a Masters in Public Policy in 2005. Selkoe also suffers from ADHD, but cites the disorder as one of the reasons he's been successful.
Greg Selkoe currently lives in Boston, Massachusetts with his wife and Creative Director at Karmaloop, Dina Selkoe.